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CAS RN: 78712-43-3 | 產品號碼: O0419
Ozagrel Hydrochloride
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* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
補充產品訊息:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| 產品號碼 | O0419 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__3H__1__2N__2O__2·HCl = 264.71 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 78712-43-3 |
| 相關CAS RN | 82571-53-7&189224-26-8 |
| Reaxys-RN | 5173590 |
| PubChem Substance ID | 253659529 |
| Merck Index(14) | 6980 |
| MDL編號 | MFCD06795644 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | 5.0 to 8.0 % |
性質
| 熔點 | 217 °C |
| 水溶性 | Soluble |
| Degree of solubility in water | 181 g/l 37 °C |
| 溶解性（微溶於） | Ethanol |
| 溶解性（不溶於） | Ether |
GHS
相關法規
| RTECS # | UD3380000 |
運輸資料
| HS編碼* | 2933.29-000 |
Application
強力かつ選択的なトロンボキサンA2合成酵素 (TXA2合成酵素) 阻害剤，オザグレル
Thromboxane A2 (TXA2) is an important metabolite of arachidonic acid cascade involved in a variety of cellular functions and diseases. TXA2 synthase activity is selectively inhibited by Ozagrel.
References
- Highly selective inhibitors of thromboxane synthetase. 1. Imidazole derivatives
- Effect of thromboxane A2 inhibitors on allergic pulmonary inflammation in mice
- Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase
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