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CAS RN: 63612-50-0 | 產品號碼: N1212
Nilutamide
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 1G |
NT$5,280
|
5 | 0 | 下單後約3-4週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | N1212 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__2H__1__0F__3N__3O__4 = 317.22 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 63612-50-0 |
| Reaxys-RN | 841906 |
| PubChem Substance ID | 468592515 |
| MDL編號 | MFCD00864670 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| Melting point | 153.0 to 157.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 155 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 : Toxic if swallowed. H360 : May damage fertility or the unborn child. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | NI9453300 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2933.29-000 |
Application
Nilutamide: A Nonsteroidal Anti-Androgen
Nilutamide is a nonsteroidal anti-androgen with affinity for androgen receptors but not for progestogen, estrogen, or glucocorticoid receptors. In vivo, nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens. Therefore, nilutamide is used in the treatment of prostate cancer, which is known to be androgen sensitive. (The product is for research purpose only.)
References
- Nilutamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer
- Receptor affinity and potency of non-steroidal antiandrogens: translation of preclinical findings into clinical activity (a review)
- Square wave adsorptive stripping voltammetric determination of anticancer drug nilutamide nilutamide in biological fluids using cationic surfactant cetyltrimethylammonium bromide
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