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CAS RN: 56391-57-2 | 產品號碼: N1108
產品號碼 | N1108 |
純度/分析方法 | >98.0%(HPLC) |
分子式 / 分子量 | C__2__1H__4__1N__5O__7·2^^1/__2H__2SO__4 = 720.77 |
外觀與形狀(20°C) | Solid |
儲存條件 | Refrigerated (0-10°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 | 100MG-Glass Bottle with Plastic Insert (閲覽圖片), 25MG-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 56391-57-2 |
相關CAS RN | 56391-56-1 |
Reaxys-RN | 5710471 |
PubChem Substance ID | 354335742 |
Merck Index(14) | 6479 |
MDL編號 | MFCD01311715 |
產品規格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC)(CAD) | min. 98.0 area% |
Specific rotation [a]20/D | +87.0 ~ +96.0 deg(C=3, water, calcd.on dried substance) |
Water | max. 15.0 % |
NMR | confirm to structure |
性質
比旋光 [α]D | 91° (C=3,H2O,calcd.on dried substance) |
GHS
圖形表示 | |
信號詞 | Danger |
危險性說明 | H360 : May damage fertility or the unborn child. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
RTECS # | WK2286000 |
運輸資料
HS編碼* | 2941.90-000 |
Application
Netilmicin Sulfate: An Aminoglycoside Antibiotic with Less Ear and Kidney Toxicity
Netilmicin sulfate, a semisynthetic 1-N-ethyl derivative of sisomicin sulfate [I1049], is an aminoglycoside antibiotic with action similar to gentamicin sulfate [G0383], but less ear and kidney toxicity. Netilmicin is active against most Gram-negative and Gram-positive Staphylococcus, including many gentamicin-resistant strains. Netilmicin interacts with the 30S subunit of bacterial ribosomes, and then it inhibits bacterial growth by inhibiting protein synthesis. (The product is for research purpose only.)
References
- Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance
- Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use (a review)
- Determination of netilmicin sulfate by liquid chromatography with pulsed electrochemical detection
- Development and Validation of a RP-HPLC Method for the Estimation of Netilmicin Sulfate and its Related Substances using Charged Aerosol Detection
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