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CAS RN: 77191-36-7 | 產品號碼: N0996
| 產品號碼 | N0996 |
| 純度/分析方法 | >98.0%(N) |
| 分子式 / 分子量 | C__1__4H__1__8N__2O__2 = 246.31 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 77191-36-7 |
| Reaxys-RN | 6848330 |
| PubChem Substance ID | 253660872 |
| Merck Index(14) | 6439 |
| MDL編號 | MFCD00209882 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 149.0 to 153.0 °C |
性質
| 熔點 | 151 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | UX9655650 |
運輸資料
| HS編碼* | 2933.79-000 |
Application
ピロリドン系の向知性剤，ネフィラセタム
Nefiracetam (DM-9384) is a pyrrolidone nootropic agent being developed for the treatment of Alzheimer's type and poststroke vascular-type dementia. It has shown the ability to increase the activity of choline acetyltransferase in the hippocampus of animals. In addition, nefiracetam enhances the activity of neuronal L-type calcium channels under the regulation of inhibitory G-proteins and cyclic AMP-dependent processes. (The product is for research purpose only.)
References
- Enhancement of neuronal calcium channel currents by the nootropic agent, nefiracetam (DM-9384), in NG108-15 cells
- Improvement by nefiracetam of β-amyloid-(1-42)-induced learning and memory impairments in rats
- Mechanisms of action of cognitive enhancers on neuroreceptors (a review)
- Pharmacological study on Alzheimer's drugs targeting calcium/calmodulin-dependent protein kinase II (a review)
考研文獻
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