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CAS RN: 61-68-7 | 產品號碼: M1782
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 230 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. H371 : May cause damage to organs. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | CB4550000 |
運輸資料
| HS編碼* | 2922.49-000 |
Application
Mefenamic Acid: A Non-Selective Non-Steroidal Anti-Inflammatory Drug (NSAID)
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. It is a non-selective cyclooxygenase (COX) inhibitor. COX directs the formation of several key mediators of inflammation called prostaglandins. Thus, mefenamic acid reduces the synthesis of prostaglandins. Mefenamic acid is metabolized principally by CYP2C9. Recently, some unique biological properties of mefenamic acid have also been reported. (The product is for research purpose only.)
References
- Inhibition of prostaglandin biosynthesis
- Selective COX-2 inhibitors: a review of their structure-activity relationships (a review)
- Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism
- The potential and promise of mefenamic acid (a review)
考研文獻
文章/手冊
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