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CAS RN: 747-36-4 | 產品號碼: H1306
Hydroxychloroquine Sulfate
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 5G |
NT$3,160
|
25 | ≥100 |
| 25G |
NT$10,480
|
5 | 14 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
補充產品訊息:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| 產品號碼 | H1306 |
| 純度/分析方法 | >98.0%(HPLC)(N) |
| 分子式 / 分子量 | C__1__8H__2__6ClN__3O·H__2SO__4 = 433.95 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 747-36-4 |
| 相關CAS RN | 118-42-3 |
| Reaxys-RN | 7242072 |
| PubChem Substance ID | 125307498 |
| SDBS (AIST Spectral DB) | 52824 |
| Merck Index(14) | 4818 |
| MDL編號 | MFCD00078203 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| NMR | confirm to structure |
性質
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H319 : Causes serious eye irritation. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | KK3342500 |
運輸資料
| HS編碼* | 2933.49-000 |
Application
Adeno-associated virus vector transduction enhancer
Hydroxychloroquine increases transduction by adeno-associated virus (AAV) vectors.1)
References
- 1) Enhancement of adeno-associated virus-mediated gene therapy using hydroxychloroquine in murine and human tissues
Application
Hydroxychloroquine Sulfate: A Derivative of 4-Aminoquinoline with Autophagy Inhibitory, Antimalarial and Anticancer Activities
Hydroxychloroquine sulfate is a derivative of 4-aminoquinoline, which is an inhibitor of autophagy and has antimalarial, anticancer and anti-rheumatoid activities. The mechanism of action of chloroquine is not completely understood. But, some studies have demonstrated that hydroxychloroquine is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. In addition, while hydroxychloroquine can inhibit certain enzymes, its effect is believed to result, at least in part from its interaction with DNA. (The product is for research purpose only.)
References
- The Role of Autophagy in Cancer: Therapeutic Implications
- Targeting autophagy in cancer (a review)
- Antimalarial Agents: Chloroquine, Hydroxychloroquine, and Quinacrine (a review)
- Hydroxychloroquine: from malaria to autoimmunity
- Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications
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