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CAS RN: 52-86-8 | 產品號碼: H0912
Haloperidol
包裝 | 價格 | 同一天 | 2-3个工作日 |
---|---|---|---|
5G |
NT$1,640
|
17 | 6 |
25G |
NT$4,920
|
26 | ≥60 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
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產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Solubility in Acetic acid | almost transparency |
Melting point | 150.0 to 153.0 °C |
性質
熔點 | 152 °C |
水溶性 | Insoluble |
溶解性(可溶於) | Benzene, Acetone, Chloroform |
GHS
圖形表示 | |
信號詞 | Danger |
危險性說明 | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H360 : May damage fertility or the unborn child. H362 : May cause harm to breast-fed children. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
RTECS # | EU1575000 |
運輸資料
UN編號 | UN2811 |
類別 | 6.1 |
包裝類別 | III |
HS編碼* | 2933.39-000 |
Application
Efflux Pump research
References
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis
- Repurposing pantoprazole and haloperidol as efflux pump inhibitors in azole resistant clinical Candida albicans and non-albicans isolates
Application
Haloperidol: A Dopamine Receptor (D2) and a Serotonin Receptor (5-HT2) Antagonist
Haloperidol is a butyrophenone series of neurotransmitter agent. The precise mechanism of action has not been clearly established, but it has been shown to be a dopamine receptor (D2) and a serotonin receptor (5-HT2) antagonist. Therefore, haloperidol is classified as a neuroleptic. Haloperidol is metabolized by several routes including the cytochrome P450 enzyme system (particularly CYP3A4 or CYP2D6). Hence, haloperidol inhibits the metabolism of tricyclic antidepressants such as doxepin hydrochloride [D4626] and imipramine hydrochloride [I0971] , increasing the blood levels of these agents. Haloperidol has no anti-histaminergic or anticholinergic activity. Haloperidol is almost insoluble in water, but is soluble in most organic solvents. (The product is for research purpose only.)
References
- Serotonergic involvement in haloperidol-induced catalepsy
- A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex
- Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist
- Pharmacokinetics of haloperidol: an update (a review)
- Antipsychotic drugs and neuroplasticity: insights into the treatment and neurobiology of schizophrenia (a review)
考研文獻
文章/手冊
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