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CAS RN: 108321-42-2 | 產品號碼: G0349
補充產品訊息:
This product has not been tested for potency and is guaranteed for chemical purity.
產品號碼 | G0349 |
純度/分析方法 | >90.0%(HPLC)(N) |
分子式 / 分子量 | C__2__0H__4__0N__4O__1__0·2H__2SO__4 = 692.70 |
外觀與形狀(20°C) | Solid |
儲存條件 | Refrigerated (0-10°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 | 1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 108321-42-2 |
相關CAS RN | 49863-47-0 |
PubChem Substance ID | 125307225 |
MDL編號 | MFCD00058314 |
產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 90.0 area% |
Purity(with Total Nitrogen) | min. 90.0 % |
Specific rotation [a]20/D | +110 to +120 deg(C=0.3, H2O, calcd.on anh.substance) |
性質
比旋光 [α]D | 111° (C=0.3,H2O) |
GHS
相關法規
運輸資料
HS編碼* | 2941.90-000 |
Application
G418: A Selective Agent for Genetically Engineered Eukaryotic Cells
G418 is an aminoglycoside antibiotic similar in structure to gentamicin [G0383] and is frequently used to selective agent for genetically engineered eukaryotic cells after transfection or transduction. It binds with the 70s and 80s ribosomes, and then it inhibits eukaryotic cell growth by inhibiting protein synthesis.
References
- A new dominant hybrid selective marker for higher eukaryotic cells
- Efficient selection for high-expression transfectants with a novel eukaryotic vector
- New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
- Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene expression
- Expression of GFP using Pichia pastoris vectors with zeocin or G-418 sulphate as the primary selectable marker
考研文獻
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