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CAS RN: 167933-07-5 | 產品號碼: F1239
| 產品號碼 | F1239 |
| 純度/分析方法 | >97.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__2__1F__3N__4O = 390.41 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 500MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 167933-07-5 |
| Reaxys-RN | 8942243 |
| PubChem Substance ID | 468591871 |
| MDL編號 | MFCD00918402 |
產品規格
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 161.0 to 165.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 163 °C |
| 水溶性 | Insoluble |
| Degree of solubility in water | 4.312 mg/l 25 °C |
| 溶解性（可溶於） | Acetone |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
| RTECS # | DE2557500 |
運輸資料
| HS編碼* | 2933.59-000 |
Application
Flibanserin: A Multimodal Serotonergic Agent
Flibanserin is a multimodal serotonergic agent that has a preferential affinity for serotonin 5-HT1A, dopamine D4, and serotonin 5-HT2A receptors. In vitro studies has suggested that flibanserin acts as a 5-HT1A agonist, a very weak partial agonist on dopamine D4 receptors, and 5-HT2A antagonist. And then, flibanserin is believed to show antipsychotic effects by increasing levels of dopamine and noradrenaline and lowering levels of serotonin in the brain. (The product is for research purpose only.)
References
- Pharmacology of flibanserin (a review)
- Multifunctional pharmacology of flibanserin: possible mechanism of therapeutic action in hypoactive sexual desire disorder (a review)
- Flibanserin: First Global Approval (a review)
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