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CAS RN: 219773-47-4 | 產品號碼: E1224
Ecabet Sodium Hydrate
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| 產品號碼 | E1224 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__2__7NaO__5S·5H__2O = 492.56 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 219773-47-4 |
| PubChem Substance ID | 468591689 |
| MDL編號 | MFCD28009632 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(Neutralization titration) | min. 98.0 % |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | +58.0 to +62.0 deg(C=0.5, water) |
| Water | 17.0 to 19.0 % |
| NMR | confirm to structure |
性質
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2916.39-000 |
Application
Ecabet Sodium: An Antiulcer and Gastroprotective Agent with Urease Inhibitory Activity
Ecabet sodium (TA-2711) is an antiulcer and gastroprotective agent. Many studies have indicated that ecabet sodium prevents the esophageal lesion by the inhibition of pepsin activity of gastric juice as well as the protection of the degradation of mucus, a defensive factor of mucosa. In addition, ecabet sodium shows bactericidal activity against H. pylori in acidic environments with inhibition of urease activity. (The product is for research purpose only.)
References
- Effects of the new antiulcer drug ecabet sodium (TA-2711) on pepsin activity. I. Inactivation of enzyme protein
- Effects of the new anti-ulcer drug ecabet sodium (TA-2711) on pepsin activity II. Interaction with substrate protein
- Ecabet sodium: a potential new agent in the management of distal colitis (a review)
- Ecabet sodium, a locally acting antiulcer drug, inhibits urease activity of Helicobacter pylori
- Chemistry and mechanism of urease inhibition (a review)
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