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CAS RN: 212322-56-0 | 產品號碼: E1033
Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate
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![Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate")
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產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 104.0 to 108.0 °C |
性質
| 熔點 | 106 °C |
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2933.39-000 |
Application
A Synthetic Intermediate of Dabigatran and Its Derivatives
This product has been used as a synthetic intermediate of dabigatran [D5902, D5904 (Etexilate)] and its derivatives, which are direct thrombin inhibitors.
References
- Structure-based design of novel potent nonpeptide thrombin inhibitors
- Synthesis, characterization and suppression of impurities during optimization of Dabigatran etexilate
- Design, synthesis and structural exploration of novel fluorinated dabigatran derivatives as direct thrombin inhibitors
- Gradient RP-HPLC method for the determination of potential impurities in dabigatran etexilate in bulk drug and capsule formulations
考研文獻
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