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CAS RN: 522-17-8 | 產品號碼: D5646
產品規格
Appearance | White to Yellow to Green powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Specific rotation | -59.0 to -63.0 deg(C=1, methanol) |
NMR | confirm to structure |
性質
熔點 | 87 °C |
Maximum Wavelength | 314(MeOH) nm |
GHS
相關法規
RTECS # | DX1500000 |
運輸資料
HS編碼* | 2932.99-000 |
Application
Deguelin: a naturally occurring rotenoid and an Akt inhibitor
Deguelin is a naturally occurring rotenoid of the flavonoid family contained in several plant species belonging to the legume family such as Derris trifoliata Lour, and has been used as a naturally occurring insecticide. In vitro and in vivo studies suggests that deguelin exerts potent anticancer activity against multiple cancer types and exhibits chemopreventive potential in Akt-inducible transgenic mouse models. (The product is for research purpose only.)
References
- Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
- Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
- Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential (a review)
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