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CAS RN: 1087737-96-9 | 產品號碼: D4295
5,6-Dichlorobenzimidazole Hydrochloride
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| 產品號碼 | D4295 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__7H__4Cl__2N__2·HCl = 223.48 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1087737-96-9 |
| PubChem Substance ID | 253660359 |
| MDL編號 | MFCD16810292 |
產品規格
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
| 溶解性（微溶於） | Methanol |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
5,6-Dichlorobenzimidazole Hydrochloride: For the Preparation of 5,6-Dichlorobenzimidazole 1-β-D-Ribofuranoside (DRB) [D4292], and etc.
5,6-Dichlorobenzimidazole hydrochloride is a starting compound for the preparation of 5,6-dichlorobenzimidazole 1-β-D-ribofuranoside (DRB) [D4292], which is a powerful inhibitor of casein kinase-2 (CK-2). 5,6-Dichlorobenzimidazole is also used to synthesize antibacterial benzimidazoles, and etc.
References
- Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1
- Synthesis of Nucleosides
- High-Throughput Five Minute Microwave Accelerated Glycosylation Approach to the Synthesis of Nucleoside Libraries
- Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents
- Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists
考研文獻
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