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CAS RN: 33818-15-4 | 產品號碼: C3445
Cytidine 5'-Diphosphocholine Sodium Salt
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| 產品號碼 | C3445 |
| 純度/分析方法 | >98.0%(HPLC) |
| 分子式 / 分子量 | C__1__4H__2__5N__4NaO__1__1P__2 = 510.31 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (<0°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic,Heat Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 33818-15-4 |
| 相關CAS RN | 987-78-0 |
| Reaxys-RN | 4110040 |
| PubChem Substance ID | 468591112 |
| MDL編號 | MFCD00037486 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | max. 6.0 % |
性質
| 熔點 | 250 °C(dec.) |
| 比旋光 [α]D | 12.5° (C=1.0,H2O) |
| Maximum Wavelength | 280(HCl aq.) nm |
GHS
相關法規
運輸資料
| HS編碼* | 2934.99-000 |
Application
Citicoline: An Intermediate in the Biosynthesis of Cell Membrane Phospholipids Acting as a Neuroprotective Agent
Citicoline (cytidine 5'-diphosphocholine, CDP-choline) is an intermediate in the biosynthesis of cell membrane phospholipids. Therefore, citicoline can activate the biosynthesis of phospholipids in the neuronal membrane, increase cerebral metabolism and increase the level of various neurotransmitters, such as acetylcholine [A0084 (chloride)] and dopamine [A0305 (hydrochloride)]. Citicoline has shown beneficial effects in various central nervous system (CNS) injury models and neurodegenerative diseases, such as stroke, brain trauma, and Parkinson's disease. (The product is for research purpose only.)
References
- Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline (a review)
- Citicoline: neuroprotective mechanisms in cerebral ischemia
- Cytidine 5'-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
- Spectrophotometric determination of Citicoline sodium in pure form and pharmaceutical formulation
- Stability indicating LC method for the determination of citicoline sodium in injection formulation
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