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Published TCIMAIL newest issue No.197 | Notice of Discontinuing the Use of Password-Protected Compressed Files | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 2030-63-9 | 產品號碼: C2866
| 產品號碼 | C2866 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__7H__2__2Cl__2N__4 = 473.40 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 2030-63-9 |
| Reaxys-RN | 60420 |
| PubChem Substance ID | 253661510 |
| Merck Index(14) | 2373 |
| MDL編號 | MFCD00056793 |
產品規格
| Appearance | Yellow to Amber to Dark red powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
性質
| 熔點 | 219 °C |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Chloroform, Dimethylformamide |
| 溶解性（微溶於） | Ether, Acetone |
GHS
| 危險性說明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相關法規
| RTECS # | SG1578000 |
運輸資料
| HS編碼* | 2933.99-000 |
Application
Clofazimine: A Lipophilic Riminophenazine Antibiotic
Clofazimine, a lipophilic riminophenazine antimicrobial, possesses both antimycobacterial and anti-inflammatory activities， and used in the treatment of mycobacterial diseases including leprosy. The antibiotic properties of clofazimine are not fully described. However, clofazimine works by binding to the bacterial DNA, thereby inhibiting bacterial proliferation. (The product is for research purpose only.)
References
- The pharmacology, metabolism, and chemistry of clofazimine (a review)
- Antimycobacterial activities of riminophenazines (a review)
- Effective treatment of acute and chronic murine tuberculosis with liposome-encapsulated clofazimine
- Reduction of Clofazimine by Mycobacterial Type 2 NADH:Quinone Oxidoreductase: A Pathway for the Generation of Bactericidal Levels of Reactive Oxygen Species
- Clofazimine: current status and future prospects (a review)
考研文獻
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