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CAS RN: 39524-08-8 | 產品號碼: A3635
Asperosaponin VI
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| 產品號碼 | A3635 |
| 純度/分析方法 | >95.0%(HPLC) |
| 分子式 / 分子量 | C__4__7H__7__6O__1__8 = 929.11 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (-20°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 39524-08-8 |
| Reaxys-RN | 5224820 |
| MDL編號 | MFCD25371916 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | +15.0 ～ +19.0 deg(C=1, methanol) |
| Water | max. 5.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 223 °C |
GHS
相關法規
| RTECS # | RK0177586 |
運輸資料
| HS編碼* | 2938.90-000 |
Application
Asperosaponin VI: A Bioactive Saponin Found in the Medicinal Herb Dipsacus asper Wall
Asperosaponin VI is a kind of saponin found in the medicinal herb Dipsacus asper Wall, which has long been used as a traditional Chinese herbal medicine for the therapy of bone diseases such as osteoporosis.1) It has been reported that asperosaponin VI has many pharmacological effects, such as neuroprotective, cardioprotective, osteoprotective, anti-apoptosis.2-4) (The product is for research purpose only.)
References
- Traditional uses, processing methods, phytochemistry, pharmacology and quality control of Dipsacus asper Wall. ex C.B. Clarke: A review
- Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways
- Asperosaponin VI, A Saponin Component from Dipsacus asper Wall, induces Osteoblast Differentiation through Bone Morphogenetic Protein-2/p38 and Extracellular Signal-regulated Kinase 1/2 Pathway
- Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway
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