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CAS RN: 23680-84-4 | 產品號碼: A2151
4-Amino-2-chloro-6,7-dimethoxyquinazoline
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 5G |
NT$1,000
|
4 | 聯繫我們 |
| 25G |
NT$3,160
|
1 | 4 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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洽詢。
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
性質
| 熔點 | 302 °C(dec.) |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
A Synthetic Intermediate of α1-Adrenoceptor Antagonists
This product is used as a synthetic intermediate of α1-adrenoceptor antagonists such as doxazosin mesylate [D4126]1-3) and terazosin hydrochloride [T2751]4).
References
- 1) 2,4-Diamino-6,7-dimethoxyquinazolines. 1. 2-[4-(1,4-Benzodioxan-2-ylcarbonyl)piperazin-1-yl] derivatives as α1-adrenoceptor antagonists and antihypertensive agents
- S. F. Campbell, M. J. Davey, J. D. Hardstone, B. N. Lewis, M. J. Palmer, J. Med. Chem. 1987, 30, 49.
- 2) Practical chemical and enzymatic technologies for (S)-1,4-benzodioxan-2-carboxypiperizine intermediate in the synthesis of (S)-doxazosin mesylate
- 3) A reliable multigram synthesis of (±) doxazosin
- 4) 4-amino-2[4-[1-(benzyloxycarbonyl)-2(S)-[[(1,1-dimethylethyl)amino]carbonyl]-piperazinyl]-6,7-dimethoxyquinazoline (L-765,314): A potent and selective α1b adrenergic receptor antagonist
考研文獻
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