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CAS RN: 957-68-6 | 產品號碼: A1266

7-Aminocephalosporanic Acid


纯度/分析方法: >97.0%(T)(HPLC)
別名
  • 7-ACA
文件:
5G
NT$3,240
≥40  0   下單後約2週內可以出貨
25G
NT$11,320
12   20   下單後約2週內可以出貨

* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與 當地經銷商 洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準,敬請留意。


產品號碼 A1266
純度/分析方法 >97.0%(T)(HPLC)
分子式 / 分子量 C__1__0H__1__2N__2O__5S = 272.28 
外觀與形狀(20°C) Solid
儲存條件 Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 957-68-6
PubChem Substance ID 87562732
Merck Index(14) 434
MDL編號

MFCD00005177

產品規格
Appearance White to Light yellow to Light orange powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Neutralization titration) min. 97.0 %
Specific rotation [a]20/D +88.0 to +94.0 deg(C=0.5, buffer sol.pH7.0 KH2PO4)
性質
比旋光 [α]D 90° (C=0.5,buffer sol. pH7.0 KH2PO4)
GHS
圖形表示 Pictogram
信號詞 Danger
危險性說明 H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
防範說明 P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P272 : Contaminated work clothing should not be allowed out of the workplace.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P284 : Wear respiratory protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
相關法規
運輸資料
HS編碼* 2934.99-000
*此H.S.編碼用於日本出口報關, 不適用於您所在國家或地區的進口申報
Application
7-Aminocephalosporanic Acid (7-ACA): a Starting Compound for Semisynthetic Cephalosporin Antibiotics.

The enzymatic conversion of cephalosporin C gives 7-aminocephalosporanic acid (7-ACA) [A1266], which is used as a starting compound for semisynthetic cephalosporin antibiotics. Modification of 7-ACA at the 3- and 7-positions gives rise to a number of third and fourth semisynthetic cephalosporin antibiotics that are significantly generally more active against Gram-negative bacteria than first and second generation ones. Differences in side chain structure at the 7-position directly affect their antibiotic activity, whereas modifications made at the 3-position influence their metabolism and pharmacokinetic properties of the drugs.

References


考研文獻


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