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CAS RN: 51-55-8 | 產品號碼: A0754
Atropine
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 5G |
NT$5,280
|
16 | 26 |
| 25G |
NT$17,520
|
9 | 1 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | A0754 |
| 純度/分析方法 | >99.0%(T) |
| 分子式 / 分子量 | C__1__7H__2__3NO__3 = 289.38 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Light Sensitive,Air Sensitive |
| CAS RN | 51-55-8 |
| Reaxys-RN | 91256 |
| PubChem Substance ID | 87562295 |
| SDBS (AIST Spectral DB) | 7817 |
| Merck Index(14) | 875 |
| MDL編號 | MFCD00022622 |
產品規格
| Appearance | White powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 99.0 % |
| Melting point | 114.0 to 118.0 °C |
| Solubility in Methanol | almost transparency |
性質
| 熔點 | 116 °C |
| Degree of solubility in water | 2.2 g/l 25 °C |
| 溶解性（可溶於） | Methanol, Benzene |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 + H331 : Toxic if swallowed or if inhaled. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相關法規
| RTECS # | CK0700000 |
運輸資料
| UN編號 | UN1544 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2939.79-000 |
Application
Atropine: A Nonselective Muscarinic Acetylcholinergic Receptors Antagonist
Atropine, a tropane alkaloid, is a free base of its sulfate [A0550] which was first extracted from the root of belladonna (Atropa belladonna) in 1830s. Atropine is a enantiomeric mixture of (R,S)-hyoscyamine (dl-hyoscyamine), racemization occurring during the extraction procedure, whereas only (S)-hyoscyamine (l-hyoscyamine) [H0450] is the active isomer. Atropine is a competitive antagonist of muscarine-like actions of acetylcholine and is therefore classified as an antimuscarinic agent. Atropine does not distinguish among the M1, M2, and M3 subgroups of muscarinic receptors. Atropine inhibits the action of acetylcholine at postganglionic nerve endings, thus affecting receptors of the exocrine glands, smooth muscle, cardiac muscle and the central nervous system. (The product is for research purpose only.)
References
- Muscarinic antagonists in development for disorders of smooth muscle function (a review)
- Atropine (a review on the chemical and physical properties, isolation, synthesis, methods of analysis, and pharmacology of atropine)
- High-performance liquid chromatographic determination of atropine and atropine-like alkaloids in pharmaceutical preparations with indirect conductometric detection
- Determination of atropine in pharmaceutical preparations by liquid chromatography with fluorescence detection
- Analysis of atropine, its degradation products and related substances of natural origin by means of reversed-phase high-performance liquid chromatography
考研文獻
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