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CAS RN: 69388-84-7 | Product Number: U0159
Sulbactam Sodium

Purity: >98.0%(T)(HPLC)
Synonyms:
- Sodium (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-Dioxide
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
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1G |
NT$5,544
|
18 | 0 | Contact Us | |
5G |
NT$18,900
|
21 | 0 | Contact Us |
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Product Number | U0159 |
Purity / Analysis Method ![]() |
>98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__8H__1__0NNaO__5S = 255.22 |
Physical State (20 deg.C) | Solid |
Storage Temperature ![]() |
Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
Packaging and Container ![]() |
1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 69388-84-7 |
Reaxys Registry Number | 3599871 |
MDL Number | MFCD01750374 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Specific rotation | +219 to +233 deg(C-1, water) |
Water | max. 1.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 190 °C |
GHS
Related Laws:
RTECS# | XH9220000 |
Transport Information:
H.S.code* | 2941.90-000 |
Application
Sulbactam Sodium: A β-Lactamase Inhibitor Used with Another Antibiotic
Sulbactam [S0868] and its sodium salt are β-lactamase inhibitors which are chemically synthesized from 6-APA [A0800]. Although they have low antimicrobial activity, they inhibit enzymes (β-lactamases) which are produced by bacteria to degrade β-lactam antibiotics such as penicillins and cephalosporins. They are often used in combination with amoxicillin [A2099] or cefoperazone [C2768] to increase the antibiotic spectrum of theirs. (The product is for research purpose only.)
References
- Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important β-lactamases
- A Structure-Based Analysis of the Inhibition of Class A β-Lactamases by Sulbactam
- Inhibitor-resistant TEM β-lactamases: phenotypic, genetic and biochemical characteristics (a review)
- Understanding the longevity of the β-lactam antibiotics and of antibiotic/β-lactamase inhibitor combinations (a review)
- Current challenges in antimicrobial chemotherapy: focus on β-lactamase inhibition (a review)
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