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CAS RN: 1508-75-4 | Product Number: T1470
Tropicamide
Purity: >99.0%(T)(HPLC)
Synonyms:
- N-Ethyl-N-(4-pyridylmethyl)tropamide
Product Documents:
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Product Number | T1470 |
Purity / Analysis Method | >99.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__7H__2__0N__2O__2 = 284.36 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 1508-75-4 |
Reaxys Registry Number | 285563 |
PubChem Substance ID | 87577232 |
Merck Index (14) | 9780 |
MDL Number | MFCD00058580 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 99.0 area% |
Purity(Nonaqueous Titration) | min. 99.0 % |
Melting point | 97.0 to 100.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 98 °C |
Maximum Absorption Wavelength | 254(HCl aq.) nm |
Solubility (soluble in) | Chloroform, Ethanol |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
RTECS# | CY1487860 |
Transport Information:
H.S.code* | 2933.39-000 |
Application
Tropicamide: A Muscarinic M4 Receptor Antagonist
Tropicamide is a muscarinic M4 receptor antagonist. Tropicamide produces short acting cycloplegia and mydriasis when applied as eye drops. Tropicamide has an action similar to atropine [A0754], but its cycloplegic and mydriatic effects have a more rapid onset and a shorter duration of effect. Tropicamide is slightly soluble in water and in diethyl ether, freely soluble in ethanol and in chloroform. (The product is for research purpose only.)
References
- The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors
- The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide
- Preparation and evaluation of liposomal formulations of tropicamide for ocular delivery
- Tropicamide (a review on the physical properties, synthesis, stability, metabolism and analysis)
- High-performance liquid chromatographic determination of phenylephrine and tropicamide in human aqueous humor
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