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CAS RN: 18059-10-4 | Product Number: P2609
Peiminine
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Purity: >97.0%(HPLC)
Synonyms:
- Verticinone
- (3β,5α)-3,20-Dihydroxycevan-6-one
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
NT$4,760
|
4 | 10 | It can be shipped in about 2 weeks after ordering | |
| 50MG |
NT$16,480
|
8 | 10 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | P2609 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__4__3NO__3 = 429.65 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 18059-10-4 |
| Reaxys Registry Number | 96785 |
| PubChem Substance ID | 468592633 |
| Merck Index (14) | 4926 |
| MDL Number | MFCD00210542 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 97.0 area% |
| Specific rotation [a]20/D | -68.0 to -76.0 deg(C=0.5, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 137 °C |
| Specific Rotation | -72° (C=0.5,MeOH) |
| Maximum Absorption Wavelength | 288(EtOH) nm |
GHS
Related Laws:
| RTECS# | FL5795000 |
Transport Information:
| H.S.code* | 2939.79-000 |
Application
Peiminine: A Bioactive Alkaloid with Antitussive, Expectorant and Anti-Inflammatory Activities
Peiminine (verticinone) and peimine (verticine) [P2610] are major active alkaloids isolated from the bulbs of Fritillaria ussuriensis, which is an Asian species of herbaceous plant in the lily family and a commonly used antitussive traditional Chinese medicinal (TCM) herb.1,2) It has been reported that peiminine and peimine also exhibit potent antitussive, expectorant and anti-inflammatory effects.3) In addition, peiminine can induce cancer cell apoptosis and autophagy.4,5) (The product is for research purpose only.)
References
- 1) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high-performance liquid chromatography coupled with evaporative light scattering detection
- 2) Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
- 3) Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae
- 4) Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves
- 5) The natural product peiminine represses colorectal carcinoma tumor growth by inducing autophagic cell death
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