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CAS RN: 174-78-7 | Product Number: O0466
2-Oxa-6-azaspiro[3.3]heptane
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![2-Oxa-6-azaspiro[3.3]heptane](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "2-Oxa-6-azaspiro[3.3]heptane")
Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
NT$9,360
|
≥40 | ≥40 |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
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* The storage conditions are subject to change without notice.
| Product Number | O0466 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__5H__9NO = 99.13 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 174-78-7 |
| Reaxys Registry Number | 18835134 |
| PubChem Substance ID | 354335112 |
| MDL Number | MFCD12407093 |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 97.0 % |
| NMR | confirm to structure |
Properties (reference)
| Flash point | 51 °C |
| Refractive Index | 1.48 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H226 : Flammable liquid and vapor. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P240 : Ground/bond container and receiving equipment. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 : Keep container tightly closed. P243 : Take precautionary measures against static discharge. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use only non-sparking tools. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P403 + P235 : Store in a well-ventilated place. Keep cool. |
Related Laws:
Transport Information:
| UN Number | UN1993 |
| Class | 3 |
| Packing Group | III |
| H.S.code* | 2934.99-000 |
Application
A Synthetic Intermediate of Bioactive Substances, such as EGFR Kinase Inhibitors and LRRK2 Inhibitors
This product is used for the synthesis of bioactive substances, such as epidermal growth factor receptor (EGFR) kinase inhibitors for cancer, and leucine rich repeat kinase 2 (LRRK2) inhibitors for Parkinson's disease.
References
- Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors
- Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor
PubMed Literature
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Safety Data Sheet (SDS)
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Specifications
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