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CAS RN: 39562-70-4 | Product Number: N1186
Nitrendipine
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 3-Ethyl 5-Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- Ethyl Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate Ethyl Methyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
NT$2,480
|
0 | 0 | It can be shipped in about 2 weeks after ordering | |
| 1G |
NT$6,560
|
13 | 0 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
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* The storage conditions are subject to change without notice.
| Product Number | N1186 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__8H__2__0N__2O__6 = 360.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 39562-70-4 |
| Reaxys Registry Number | 498823 |
| PubChem Substance ID | 468592504 |
| Merck Index (14) | 6576 |
| MDL Number | MFCD00082255 |
Specifications
| Appearance | White to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 157.0 to 161.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 159 °C |
| Maximum Absorption Wavelength | 352(MeOH) nm |
| Solubility (slightly sol. in) | Methanol, Ether |
GHS
Related Laws:
| RTECS# | US5653000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Nitrendipine: A Vascular-Selective Dihydropyridine Calcium Channel Antagonist
Nitrendipine is a vascular-selective dihydropyridine calcium channel antagonist that causes vasodilatation by blocking the influx of calcium ions through L-type calcium channels in cell membranes. It is an effective antihypertensive agent and differs from other calcium channel antagonists in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. (The product is for research purpose only.)
References
- Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state
- Nitrendipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of hypertension
- Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis
- Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry
Product Documents (Note: Some products will not have analytical charts available.)
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