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CAS RN: 77191-36-7 | Product Number: N0996
Nefiracetam
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Purity: >98.0%(N)
Synonyms:
- N-(2,6-Dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
NT$4,160
|
20 | 7 | Contact Us | |
| 1G |
NT$13,320
|
9 | 1 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | N0996 |
| Purity / Analysis Method | >98.0%(N) |
| Molecular Formula / Molecular Weight | C__1__4H__1__8N__2O__2 = 246.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 77191-36-7 |
| Reaxys Registry Number | 6848330 |
| PubChem Substance ID | 253660872 |
| Merck Index (14) | 6439 |
| MDL Number | MFCD00209882 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 149.0 to 153.0 °C |
Properties (reference)
| Melting Point | 151 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UX9655650 |
Transport Information:
| H.S.code* | 2933.79-000 |
Application
ピロリドン系の向知性剤，ネフィラセタム
Nefiracetam (DM-9384) is a pyrrolidone nootropic agent being developed for the treatment of Alzheimer's type and poststroke vascular-type dementia. It has shown the ability to increase the activity of choline acetyltransferase in the hippocampus of animals. In addition, nefiracetam enhances the activity of neuronal L-type calcium channels under the regulation of inhibitory G-proteins and cyclic AMP-dependent processes. (The product is for research purpose only.)
References
- Enhancement of neuronal calcium channel currents by the nootropic agent, nefiracetam (DM-9384), in NG108-15 cells
- Improvement by nefiracetam of β-amyloid-(1-42)-induced learning and memory impairments in rats
- Mechanisms of action of cognitive enhancers on neuroreceptors (a review)
- Pharmacological study on Alzheimer's drugs targeting calcium/calmodulin-dependent protein kinase II (a review)
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