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CAS RN: 25137-01-3 | Product Number: N0655

Ethyl (R)-(-)-3-Piperidinecarboxylate


Purity: >98.0%(GC)
Synonyms:
  • Ethyl (R)-(-)-Nipecotate
  • (R)-(-)-Nipecotic Acid Ethyl Ester
  • (R)-(-)-3-Piperidinecarboxylic Acid Ethyl Ester
Product Documents:
5G
NT$1,400
25   0   It can be shipped in about 2 weeks after ordering
25G
NT$4,520
9   0   It can be shipped in about 2 weeks after ordering

* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact our distributor in Taiwan to order our product.
* The storage conditions are subject to change without notice.


Product Number N0655
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__8H__1__5NO__2 = 157.21 
Physical State (20 deg.C) Liquid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Moisture Sensitive,Heat Sensitive
CAS RN 25137-01-3
Reaxys Registry Number 81695
PubChem Substance ID 87573967
MDL Number

MFCD03093637

Specifications
Appearance Colorless to Almost colorless clear liquid
Purity(GC) min. 98.0 %
Specific rotation [a]20/D -1.0 to -2.0 deg(neat)
NMR confirm to structure
Properties (reference)
Boiling Point 110 °C/20 mmHg
Flash point 90 °C
Specific Gravity (20/20) 1.02
Specific Rotation -1.5° (neat)
Refractive Index 1.46
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H227 : Combustible liquid.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P403 + P235 : Store in a well-ventilated place. Keep cool.
Related Laws:
Transport Information:
H.S.code* 2933.39-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
GABA再取り込み阻害剤 (R)-(-)-ニペコチン酸のプロドラッグ,(R)-(-)-ニペコチン酸エチル

Ethyl (R)-(-)-nipecotate is a prodrug of (R)-(-)-nipecotic acid [N0654] which is a γ-aminobutyric acid (GABA) reuptake inhibitor.1) In addition, some derivatives of ethyl (R)-(-)-nipecotate have been synthesized and evaluated for their bioactivity.2-4)

References


PubMed Literature


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