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CAS RN: 328086-60-8 | Product Number: M3533
Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate
Purity: >98.0%(T)(HPLC)
Synonyms:
- Methyl (S)-2-[(tert-Butoxycarbonyl)amino]-3-[(S)-2-oxopyrrolidin-3-yl]propanoate
- Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate
- (αS,3S)-α-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
5G |
NT$3,600
|
25 | 0 | Contact Us | |
25G |
NT$13,840
|
7 | 0 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
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* The storage conditions are subject to change without notice.
Product Number | M3533 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__3H__2__2N__2O__5 = 286.33 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
CAS RN | 328086-60-8 |
Reaxys Registry Number | 8991735 |
MDL Number | MFCD28138267 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Volumetric Analysis) | min. 98.0 % |
Melting point | 111.0 to 115.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 114 °C |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.79-000 |
Application
A Key Synthetic Intermediate for Antiviral Protease Inhibitors
This product has been used as a key synthetic intermediate for antiviral protease inhibitors including GC376 and nirmatrelvir.
References
- Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
- Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine
- Optimized Synthesis of a Key Intermediate of Nirmatrelvir
Product Documents (Note: Some products will not have analytical charts available.)
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