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CAS RN: 165800-03-3 | Product Number: L0362
Linezolid
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Purity: >98.0%(HPLC)
Synonyms:
- (S)-N-[[3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl]acetamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
NT$1,880
|
5 | ≥60 | Contact Us | |
| 1G |
NT$5,560
|
≥40 | 9 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | L0362 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__2__0FN__3O__4 = 337.35 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 165800-03-3 |
| Reaxys Registry Number | 7496939 |
| PubChem Substance ID | 468592166 |
| MDL Number | MFCD00937825 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 177.0 to 181.0 °C |
| Specific rotation | -7.0 to -9.0 deg(C=1, CHCl3) |
Properties (reference)
| Melting Point | 179 °C |
| Maximum Absorption Wavelength | 252(H2O) nm |
| Solubility in water | Insoluble |
| Degree of solubility in water | 610 mg/l 25 °C |
| Solubility (slightly sol. in) | dichloromethane |
| Solubility (insoluble in) | Ethanol |
GHS
| Pictogram |
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| Signal Word | Danger |
| Hazard Statements | H372 : Causes damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P314 : Get medical advice/ attention if you feel unwell. |
Related Laws:
| RTECS# | AC2720000 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Linezolid: A Synthetic Oxazolidinone Antibacterial with Excellent Activity against Gram-Positive Pathogens including Antibiotic-Resistant Bacteria
Linezolid (U-100766) is a synthetic oxazolidinone antibacterial which has excellent activity against virtually all important Gram-positive pathogens, including methicillin-resistant staphylococci (e.g. MRSA), penicillin-resistant pneumococci, macrolide-resistant streptococci, and vancomycin-resistant enterococci (VRE). In addition, the in vitro spectrum of activity of linezolid also includes certain Gram-negative bacteria and anaerobic bacteria. It has been reported that linezolid binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, which is an essential component of the bacterial translation process. In recent years, the emergence of bacteria resistant to linezolid has become a problem. (The product is for research purpose only.)
References
- In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents
- The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria
- Oxazolidinone structure-activity relationships leading to linezolid (a review)
- Linezolid: the first oxazolidinone antimicrobial (a review)
- The emerging problem of linezolid-resistant Staphylococcus (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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