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CAS RN: 304-20-1 | Product Number: H0409
1-Hydrazinophthalazine Hydrochloride
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Purity: >99.0%(T)(HPLC)
Synonyms:
- Hydralazine Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 5G |
NT$2,080
|
28 | Contact Us |
| 25G |
NT$8,080
|
14 | 1 |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | H0409 |
| Purity / Analysis Method | >99.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__8N__4·HCl = 196.64 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 304-20-1 |
| Related CAS RN | 86-54-4 |
| Reaxys Registry Number | 3568329 |
| PubChem Substance ID | 87570812 |
| Merck Index (14) | 4763 |
| MDL Number | MFCD00135998 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 99.0 area% |
| Purity( Potassium iodate Method) | min. 99.0 % |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 273 °C(dec.) |
| Solubility in water | Soluble |
| Degree of solubility in water | 44.2 g/l 25 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P260 : Do not breathe dusts or mists. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | TH9000000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2933.99-000 |
Application
Hydralazine Hydrochloride: A Vasodilator in Arterioles
Although the precise mechanism of action is not fully under-stood, hydralazine hydrochloride exerts its peripheral vasodilating effect through a direct relaxation of smooth muscle tissue in vascular resistance vessels, predominantly in the arterioles, and resulting in decreased blood pressure. Recently, the property of hydralazine has been reported, such as a DNA methylation inhibitor, an antioxidant and etc. (The product is for research purpose only.)
References
- Hydralazine and isosorbide dinitrate in heart failure: historical perspective, mechanisms, and future directions (a review)
- Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity
- Molecular Modeling and Molecular Dynamics Studies of Hydralazine with Human DNA Methyltransferase 1
- Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug
- Hydralazine hydrochloride (a review including physical properties, synthesis, stability, metabolism and methods of analyzing)
- Spectrophotometric determination of hydralazine using p-dimethylaminobenzaldehyde
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