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CAS RN: 84163-13-3 | Product Number: F0944
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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Product Number | F0944 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__2H__1__3FN__2O·HCl = 256.71 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 84163-13-3 |
Reaxys Registry Number | 5662739 |
PubChem Substance ID | 253661962 |
MDL Number | MFCD06658529 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
GHS
Pictogram |
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Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
H.S.code* | 2934.99-000 |
Application
A synthetic Intermediate of Benzisoxazole Derivatives Acting as a Dopamine D2 and 5-HT2 Receptors Antagonist
This product has been used as a synthetic intermediate of benzisoxazole derivatives which act as a dopamine type 2 (D2) and serotonin type 2 (5-HT2) receptors antagonist, such as iloperidone [I0926], paliperidone [P1897] and risperidone [R0087].
References
- 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-Benzisoxazoles as D2/5HT2 Antagonists with Potential Atypical Antipsychotic Activity: Antipsychotic Profile of Iloperidone (HP 873)
- An Improved and Efficient Process for the Production of Highly Pure Paliperidone, a Psychotropic Agent, via DBU Catalyzed N-Alkylation
- Improved and efficient process for the production of highly pure iloperidone: a psychotropic agent
PubMed Literature
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