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CAS RN: 220119-17-5 | Product Number: E1500
Selamectin
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Purity: >95.0%(HPLC)
Synonyms:
- (5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
NT$2,560
|
12 | 0 | Contact Us | |
| 1G |
NT$8,920
|
12 | 0 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | E1500 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__4__3H__6__3NO__1__1 = 769.97 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 220119-17-5 |
| Reaxys Registry Number | 10756416 |
| MDL Number | MFCD31621085 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| NMR | confirm to structure |
Properties (reference)
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| RTECS# | CL1199500 |
Transport Information:
| H.S.code* | 2932.20-000 |
Application
Selamectin: A Macrocyclic Lactone of the Avermectin Class of Anthelmintics
Selamectin is a macrocyclic lactone of the avermectin class of anthelmintics, which includes ivermectin [I0819].1,2) The mechanism of action of selamectin is not fully understood, but it is strongly suggested to be related to glutamate-gated and GABA-gated chloride channels in nematode muscles and nerves.3,4) Selamectin binds with high affinity to the nematode’s chloride channels. As a result, the nematode is believed to be paralyzed. (The product is for research purpose only.)
References
- 1) Selamectin: a novel broad-spectrum endectocide for dogs and cats (a review)
- 2) Pharmacokinetics of selamectin following intravenous, oral and topical administration in cats and dogs
- 3) Chloride channels as tools for developing selective insecticides (a review)
- 4) Avermectin derivatives, pharmacokinetics, therapeutic and toxic dosages, mechanism of action, and their biological effects (a review)
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