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CAS RN: 145108-58-3 | Product Number: D5062
Dexmedetomidine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (+)-Medetomidine Hydrochloride
- (S)-4-(α,2,3-Trimethybenzyl)-1H-imidazole Hydrochloride
- (S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 20MG |
NT$3,360
|
38 | 9 | It can be shipped in about 3-4 weeks after ordering | |
| 100MG |
NT$10,760
|
28 | 0 | It can be shipped in about 3-4 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | D5062 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__6N__2·HCl = 236.74 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 20MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 145108-58-3 |
| Related CAS RN | 113775-47-6 |
| Reaxys Registry Number | 8937629 |
| PubChem Substance ID | 354333214 |
| Merck Index (14) | 2946 |
| MDL Number | MFCD12912677 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Argentometric Titration) | min. 98.0 % |
| Melting point | 156.0 to 160.0 °C |
| Specific rotation [a]20/D | +49.0 to +54.0 deg(C=1, H2O) |
Properties (reference)
| Melting Point | 158 °C |
| Specific Rotation | 51° (C=1,H2O) |
GHS
| Pictogram |
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| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | NI5156750 |
Transport Information:
| H.S.code* | 2933.29-000 |
Application
Dexmedetomidine Hydrochloride: A Potent and Selective α2-Adrenoceptor Agonist
Dexmedetomidine hydrochloride is a potent α2-adrenoceptor agonist, which produces and analgesia, about 8 times higher selective affinity for the α2/α1-adrenoceptor than clonidine [D1353]. Dexmedetomidine also binds to imidazoline receptors, based on the imidazole group. (The product is for research purpose only.)
References
- Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes
- Further characterization of the receptor mechanism involved in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs.
- Assessment of the role of α2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice
- The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects
- Dexmedetomidine: a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation
PubMed Literature
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Safety Data Sheet (SDS)
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Specifications
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