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CAS RN: 14484-47-0 | Product Number: D4523
Deflazacort
Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
1G |
NT$3,120
|
8 | 20 |
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Product Number | D4523 |
Purity / Analysis Method | >98.0%(HPLC)(N) |
Molecular Formula / Molecular Weight | C__2__5H__3__1NO__6 = 441.52 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 14484-47-0 |
Reaxys Registry Number | 4947650 |
PubChem Substance ID | 253661789 |
Merck Index (14) | 2862 |
MDL Number | MFCD00866106 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 256.0 to 260.0 °C |
Specific rotation [a]20/D | +63.0 to +74.0 deg(C=0.5, CHCl3) |
Properties (reference)
Melting Point | 258 °C |
Specific Rotation | 73° (C=0.5,CHCl3) |
Solubility (soluble in) | dichloromethane |
GHS
Related Laws:
RTECS# | TU4157050 |
Transport Information:
H.S.code* | 2937.29-000 |
Application
Deflazacort: A Synthetic Glucocorticoid with Anti-Inflammatory and Immunosuppressive Activity
Deflazacort is a synthetic glucocorticoid and an oxazoline derivative of prednisolone [P0637] with anti-inflammatory and immunosuppressive activity. Deflazacort is an ester prodrug and metabolized to form the active metabolite 21-desacetyldeflazacort.
References
- Deflazacort. A review of its pharmacological properties and therapeutic efficacy
- Disposition of a new steroidal anti-inflammatory agent, deflazacort, in rat, dog and man
- Deflazacort: a glucocorticoid with few metabolic adverse effects but important immunosuppressive activity
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