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CAS RN: 4097-22-7 | Product Number: D3065

2',3'-Dideoxyadenosine


Purity: >98.0%(T)(HPLC)
Synonyms:
  • ddA
  • 9-(2,3-Dideoxy-β-D-ribofuranosyl)adenine
Product Documents:
100MG
NT$18,840
16   10  

* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact our distributor in Taiwan to order our product.
* The storage conditions are subject to change without notice.


Supplemental Product Information:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number D3065
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__0H__1__3N__5O__2 = 235.25 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 4097-22-7
Reaxys Registry Number 619924
PubChem Substance ID 87559802
SDBS (AIST Spectral DB) 52173
Merck Index (14) 3101
MDL Number

MFCD00010534

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 186.0 to 190.0 °C
Specific rotation [a]20/D -27.0 to -34.0 deg(C=1, H2O)
NMR confirm to structure
Properties (reference)
Melting Point 188 °C
Specific Rotation -34° (C=1,H2O)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H341 : Suspected of causing genetic defects.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# AU7358900
Transport Information:
H.S.code* 2940.00-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
2',3'-Dideoxyadenosine (ddA): A Nucleoside Reverse Transcriptase Inhibitor

2',3'-Dideoxyadenosine (ddA) and didanosine (ddI) [D3066] are nucleoside reverse transcriptase inhibitors. ddA is a synthetic nucleoside analogue of the naturally occurring nucleoside 2’-deoxyadenosine in which the 3'-hydroxyl group is replaced by hydrogen. Intracellularly, ddA and ddI are converted by cellular enzymes to the active metabolite, ddA- 5'-triphosphate. The triphosphate inhibits the activity of viral reverse transcriptase both by competing with the natural substrate, 2’-deoxyadenosine-5'-triphosphate, and by its incorporation into viral DNA causing termination of viral DNA chain. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
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