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CAS RN: 1492-18-8 | Product Number: C2235
Calcium Folinate
Purity: >98.0%(T)(HPLC)
Synonyms:
- Folinic Acid Calcium Salt
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
1G |
NT$3,200
|
6 | 7 |
5G |
NT$9,440
|
6 | ≥40 |
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* The storage conditions are subject to change without notice.
Product Number | C2235 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__2__1CaN__7O__7 = 511.51 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Hygroscopic |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 1492-18-8 |
Related CAS RN | 58-05-9&6035-45-6&2060570-47-8 |
Reaxys Registry Number | 5723924 |
PubChem Substance ID | 87560126 |
MDL Number | MFCD00006704 |
Specifications
Appearance | Light orange to Yellow to Green powder to crystaline |
Purity(HPLC) | min. 98.0 area% |
Purity(Chelometric Titration) | min. 98.0 %(calcd.on anh.substance) |
Water | max. 17.0 % |
NMR | confirm to structure |
Properties (reference)
Solubility in water | Soluble |
Solubility (insoluble in) | Ethanol |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
RTECS# | MA0600500 |
Transport Information:
H.S.code* | 2934.99-000 |
Application
Calcium folinate: a Pharmaceutical Adjuvant for Folate Antagonists and 5-Fluorouracil
Calcium folinate is used as to reduce the harmful effects of folate antagonists such as methotrexate [M1664]. Calcium folinate is also used in synergistic combination with 5-fluorouracil [F0151] to enhance of its antitumor effect.
References
- Folate supplementation and methotrexate treatment in rheumatoid arthritis: a review
- Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review
- Enhancement of the antitumor effects of 5-fluorouracil by folinic acid
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