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CAS RN: 18156-74-6 | Product Number: A5605
TMS-Imidazole (=N-Trimethylsilylimidazole) [for Gas Chromatography]
Purity: >98.0%(T)
Synonyms:
- SIM
- N-Trimethylsilylimidazole
- TMSI
Product Documents:
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Product Number | A5605 |
Purity / Analysis Method | >98.0%(T) |
Molecular Formula / Molecular Weight | C__6H__1__2N__2Si = 140.26 |
Physical State (20 deg.C) | Liquid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Moisture Sensitive,Heat Sensitive |
Packaging and Container | 5ML-Vial (View image) |
CAS RN | 18156-74-6 |
Reaxys Registry Number | 606148 |
PubChem Substance ID | 87563207 |
SDBS (AIST Spectral DB) | 19968 |
MDL Number | MFCD00005280 |
Specifications
Appearance | Colorless to Almost colorless clear liquid |
Purity(Nonaqueous Titration) | min. 98.0 % |
Effect test of TMS derivatization | Effective as derivatization agent Glucose |
High boiling impurity of Silylation agent | No impurity higher than Isopropyl myristate(50 ppm) after 5 min + hold up time |
Properties (reference)
Melting Point | -42 °C |
Boiling Point | 94 °C/14 mmHg |
Flash point | 5 °C |
Specific Gravity (20/20) | 0.96 |
Refractive Index | 1.48 |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H225 : Highly flammable liquid and vapor. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P240 : Ground/bond container and receiving equipment. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 : Keep container tightly closed. P243 : Take precautionary measures against static discharge. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use only non-sparking tools. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P403 + P235 : Store in a well-ventilated place. Keep cool. |
Related Laws:
RTECS# | NI8700000 |
Transport Information:
UN Number | UN1993 |
Class | 3 |
Packing Group | II |
H.S.code* | 3822.19-000 |
Application
Trimethylsilylating Reagent for GC
Experimental procedure:
Approx. 1 mg of a sample and SIM (1 mL) are placed in a dry vial, and then the vial is tightly sealed and allowed to react by shaking or heating.
Approx. 1 mg of a sample and SIM (1 mL) are placed in a dry vial, and then the vial is tightly sealed and allowed to react by shaking or heating.
Application
Trimethylsilylation of Alcohols using TMS Reagents
References
- Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
- P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.
PubMed Literature
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