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CAS RN: 78954-23-1 | Product Number: Y0022
Yakuchinone A
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Purity: >98.0%(HPLC)
Synonyms:
- 1-(4-Hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanone
- 1-(4-Hydroxy-3-methoxyphenyl)-7-phenylheptan-3-one
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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|---|---|---|---|---|---|
| 10MG |
$237.00
|
0 | 0 | Contact Us |
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| Product Number | Y0022 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__4O__3 = 312.41 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 78954-23-1 |
| Reaxys Registry Number | 3404294 |
| MDL Number | MFCD30533823 |
Specifications
| Appearance | Colorless to Yellow to Orange clear liquid |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 214 °C/2 mmHg |
| Flash point | 174 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2914.50-000 |
Application
Yakuchinone A: A Major Constituent of a Traditional Medicine Alpinia oxyphylla
Yakuchinone A is a major constituent of a traditional medicine Alpinia oxyphylla, and exhibits anti-inflammatory, antitumor, antibacterial, and gastric protective activities. It has been reported that yakuchinone A inhibits the expression of cyclooxygenase-2 (COX-2) and of inducible nitric oxide synthase (iNOS) as well as the expression of tumor necrosis factor (TNF)-α mRNA in mouse skin. (The product is for research purpose only.)
References
- Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae)
- Effects of yakuchinone A and yakuchinone B on the phorbol ester-induced expression of COX-2 and iNOS and activation of NF-κB in mouse skin
- Antioxidant, anti-adipocyte differentiation, antitumor activity and anthelmintic activities against Anisakis simplex and Hymenolepis nana of yakuchinone A from Alpinia oxyphylla
- Validated method to measure yakuchinone A in plasma by LC-MS/MS and its application to a pharmacokinetic study in rats
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