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CAS RN: 150322-43-3 | Product Number: P2040
Prasugrel
Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate
Product Documents:
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Product Number | P2040 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__2__0FNO__3S = 373.44 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 150322-43-3 |
Reaxys Registry Number | 9008623 |
PubChem Substance ID | 172089108 |
MDL Number | MFCD09954140 |
Specifications
Appearance | Light yellow to Yellow to Orange powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 120.0 to 124.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 122 °C |
GHS
Related Laws:
Transport Information:
H.S.code* | 2934.99-000 |
Application
Studies on the Platelet Aggregation Inhibition Activity of Prasugel
References
- Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
- Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel: Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes
- Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
- Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity
- The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
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