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CAS RN: 56180-94-0 | Product Number: A2485
Acarbose
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Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$102.00
|
7 | 0 | It can be shipped in about 2 weeks after ordering | |
| 5G |
$349.00
|
20 | 4 | It can be shipped in about 2 weeks after ordering |
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* The storage conditions are subject to change without notice.
Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | A2485 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__5H__4__3NO__1__8 = 645.61 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 56180-94-0 |
| Reaxys Registry Number | 4898350 |
| PubChem Substance ID | 160871251 |
| Merck Index (14) | 18 |
| MDL Number | MFCD00869592 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +173 to +183 deg(C=1、H2O)(calcd.on anh.substance) |
| Water | max. 5.0 % |
Properties (reference)
| Specific Rotation | 176° (C=1,H2O) |
GHS
Related Laws:
| RTECS# | LZ7153000 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Acarbose: α-Glucosidase Inhibitor
Acarbose, a complex oligosaccharide, is obtained from fermentation processes of a microorganism, Actinoplanes utahensis. Acarbose acts by competitive and reversible inhibition of intestinal α-glucosidases and α-amylase which are enzymes responsible for the metabolite of complex carbohydrates into absorbable monosaccharide units. This action delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. In contrast to sulfonylureas, acarbose does not enhance insulin secretion. Acarbose is used for the treatment of type 2 diabetes. (The product is for research purpose only.)
References
- Acarbose. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
- Biotechnology and molecular biology of the α-glucosidase inhibitor acarbose (a review)
- Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase
- Analysis and determination of anti-diabetes drug acarbose and its structural analogs (a review)
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