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CAS RN: 147127-20-6 | 产品编码: T3006
Tenofovir
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This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
技术规格
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0%(calcd.on anh.substance) |
| Specific rotation [a]20/D | -19.0 to -21.0 deg(C=1, 0.1mol/L HCl)(calcd.on anh.substance) |
| Water | max. 6.0 % |
物性（参考值）
| 熔点 | 283 °C |
| 比旋光度 [α]D | -20° (C=1,0.1mol/L HCl) |
GHS
相关法规
| RTECS# | SZ6563600 |
运输信息
| HS编码* | 2933.99-000 |
应用
Tenofovir: a Nucleotide Reverse Transcriptase (RT) Inhibitor
Tenofovir, also known as PMPA, is a nucleotide reverse transcriptase (RT) inhibitor. It shows activity against hepatitis B virus (HBV) and human immunodeficiency virus (HIV). It is the active metabolite of tenofovir disoproxil fumarate.
References
- Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine
- Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors
- Phosphonomethoxyalkyl analogs of nucleotides
- Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections
- Case history: Acyclic nucleoside phosphonates: a key class of antiviral drugs
参考文献
TCIMail
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技术规格
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