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CAS RN: 1041434-82-5 | 产品编码: P2892
Peramivir Trihydrate
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纯度/分析方法: >97.0%(T)(HPLC)
别名:
- 帕拉米韦 三水合物
- (1S,2S,3R,4R)-3-[(S)-1-乙酰氨基-2-乙基丁基]-4-胍基-2-羟基环戊烷-1-甲酸 三水合物
- (1S,2S,3R,4R)-3-[(1S)-1-(乙酰氨基)-2-乙基丁基]-4-[(氨基亚氨基甲基)氨基]-2羟基环戊烷甲酸 三水合物
- BCX-1812 Trihydrate
- (1S,2S,3R,4R)-3-[(S)-1-Acetamido-2-ethylbutyl]-4-guanidino-2-hydroxycyclopentane-1-carboxylic Acid Trihydrate
- (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid Trihydrate
产品文档:
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 97.0 area% |
Purity(Volumetric Analysis) | min. 97.0 % |
Specific rotation | -124 to -132 deg (C=1, water) |
NMR | confirm to structure |
物性(参考值)
水溶性 | 微溶 |
溶解性(不溶于) | 二甲基甲酰胺 |
GHS
相关法规
运输信息
HS编码* | 2925.29-000 |
应用
Peramivir: An Inhibitor of Influenza Virus Neuraminidase
Peramivir (BCX-1812, RWJ-270201) is an inhibitor of influenza virus neuraminidase, which is an enzyme that releases viral particles from the plasma membrane of infected cells. (The product is for research purpose only.)
References
- Bcx-1812 (rwj-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design
- Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses
- Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance (a review)
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技术规格
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