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CAS RN: 130-86-9 | 产品编码: P2611
Protopine
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| 产品编码 | P2611 |
| 纯度/分析方法 | >98.0%(GC) |
| 分子式/分子量 | C__2__0H__1__9NO__5 = 353.37 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 130-86-9 |
| Reaxys-RN | 97707 |
| PubChem物质ID | 354335807 |
| Merck Index (14) | 7896 |
| MDL编号 | MFCD00022322 |
技术规格
| Appearance | White to Light gray to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 201.0 to 205.0 °C |
物性（参考值）
| 熔点 | 203 °C |
| 比旋光度 [α]D | 0° (C=0.55,CHCl3) |
| 最大吸收波长 | 288 nm (MeOH) |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 8.99 mg/l 25 °C |
| 溶解性（可溶于） | 氯仿 |
| 溶解性（微溶于） | 乙醇, 苯 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | VS2800000 |
运输信息
| UN编号 | UN1544 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2939.79-000 |
应用
Protopine: An Isoquinoline Bioactive Alkaloid Isolated from Corydalis tubers
Protopine is an isoquinoline alkaloid isolated from Corydalis tubers, and has been reported to have multiple biological actions on the cardiovascular system, anti-thrombotic, anti-inflammatory, anti-spasmodic, neuroprotective, anti-bacterial, anti-viral, anti-fungal and anti-parasitic activities. (The product is for research purpose only.)
References
- The chemical and biological properties of protopine and allocryptopine (a review)
- Qualitative and quantitative determination of ten alkaloids in traditional Chinese medicine Corydalis yanhusuo W.T. Wang by LC-MS/MS and LC-DAD
- Simultaneous determination of tetrahydropalmatine, protopine, and palmatine in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study
参考文献
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