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CAS RN: 18059-10-4 | 产品编码: P2609
Peiminine
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| 产品编码 | P2609 |
| 纯度/分析方法 | >97.0%(HPLC) |
| 分子式/分子量 | C__2__7H__4__3NO__3 = 429.65 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 10MG-Glass Bottle with Plastic Insert （查看图片）, 50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 18059-10-4 |
| Reaxys-RN | 96785 |
| PubChem物质ID | 468592633 |
| Merck Index (14) | 4926 |
| MDL编号 | MFCD00210542 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 97.0 area% |
| Specific rotation [a]20/D | -68.0 to -76.0 deg(C=0.5, MeOH) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 137 °C |
| 比旋光度 [α]D | -72° (C=0.5,MeOH) |
| 最大吸收波长 | 288(EtOH) nm |
GHS
相关法规
| RTECS# | FL5795000 |
运输信息
| HS编码* | 2939.79-000 |
应用
Peiminine: A Bioactive Alkaloid with Antitussive, Expectorant and Anti-Inflammatory Activities
Peiminine (verticinone) and peimine (verticine) [P2610] are major active alkaloids isolated from the bulbs of Fritillaria ussuriensis, which is an Asian species of herbaceous plant in the lily family and a commonly used antitussive traditional Chinese medicinal (TCM) herb.1,2) It has been reported that peiminine and peimine also exhibit potent antitussive, expectorant and anti-inflammatory effects.3) In addition, peiminine can induce cancer cell apoptosis and autophagy.4,5) (The product is for research purpose only.)
References
- 1) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high-performance liquid chromatography coupled with evaporative light scattering detection
- 2) Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
- 3) Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae
- 4) Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves
- 5) The natural product peiminine represses colorectal carcinoma tumor growth by inducing autophagic cell death
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