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CAS RN: 50-24-8 | 产品编码: P0637
Prednisolone
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| 产品编码 | P0637 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__2__1H__2__8O__5 = 360.45 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 50-24-8 |
| Reaxys-RN | 1354103 |
| PubChem物质ID | 87574796 |
| SDBS (AIST Spectral DB) | 10998 |
| Merck Index (14) | 7721 |
| MDL编号 | MFCD00003649 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +97.0 to +103.0 deg(C=1, Dioxane) |
| Solubility in Dioxane | almost transparency |
物性（参考值）
| 熔点 | 235 °C |
| 比旋光度 [α]D | 100° (C=1,Dioxane) |
| 水溶性 | 不溶 |
| 溶解性（可溶于） | 甲醇, 乙醇 |
| 溶解性（微溶于） | 二噁烷, 丙酮 |
| 溶解性（不溶于） | 乙醚 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | TU4152000 |
运输信息
| HS编码* | 2937.21-000 |
应用
Prednisolone: A Synthetic Adrenocortical Steroid Agent with Predominantly Glucocorticoid Properties
Prednisolone is a synthetic adrenocortical steroid agent with predominantly glucocorticoid properties, which is used for the treatment of a wide range of inflammatory and autoimmune conditions. It is the active hepatic metabolite of prednisone [P1276]. (The product is for research purpose only.)
References
- Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition
- Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids (a review)
- Glucocorticoid action and the development of selective glucocorticoid receptor ligands (a review)
- Allergic and pseudoallergic reactions induced by glucocorticoids: A review
- Simple liquid chromatography method for the rapid simultaneous determination of prednisolone and cortisol in plasma and urine using hydrophilic lipophilic balanced solid phase extraction cartridges
参考文献
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