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CAS RN: 1470-99-1 | 产品编码: O0471
cis-Octahydroisoindole
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技术规格
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 97.0 % |
| Purity(Nonaqueous Titration) | min. 97.0 % |
物性（参考值）
| 沸点 | 189 °C |
| 闪点 | 62 °C |
| 比重 | 0.97 |
| 折射率 | 1.49 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H227 : Combustible liquid. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P403 + P235 : Store in a well-ventilated place. Keep cool. |
相关法规
运输信息
| HS编码* | 2933.99-000 |
应用
A Synthetic Intermediate of Mitiglinide Calcium (KAD-1229)
This product is used for the synthesis of mitiglinide calcium (KAD-1229) [M3177] which is an insulinotropic agent for the treatment of type 2 diabetes.
References
- Preparation of optically active succinic acid derivatives. I. Optical resolution of 2-benzyl-3-(cis-hexahydroisoindolin-2-ylcarbonyl)propionic acid
- Preparation and optically active succinic acid derivatives. II. Efficient and practical synthesis of KAD-1229
- An effective and convenient method for the preparation of KAD-1229
- Identification, synthesis and characterization of impurities of (S)-mitiglinide calcium dihydrate
参考文献
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