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CAS RN: 174-78-7 | 产品编码: O0466
2-Oxa-6-azaspiro[3.3]heptane
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![2-Oxa-6-azaspiro[3.3]heptane](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "2-Oxa-6-azaspiro[3.3]heptane")
| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 1G |
S$351.00
|
≥40 | ≥40 |
|
技术规格
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 97.0 % |
| NMR | confirm to structure |
物性（参考值）
| 闪点 | 51 °C |
| 折射率 | 1.48 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H226 : Flammable liquid and vapor. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P240 : Ground/bond container and receiving equipment. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 : Keep container tightly closed. P243 : Take precautionary measures against static discharge. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use only non-sparking tools. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P403 + P235 : Store in a well-ventilated place. Keep cool. |
相关法规
运输信息
| UN编号 | UN1993 |
| 类别 | 3 |
| 包装类别 | III |
| HS编码* | 2934.99-000 |
应用
A Synthetic Intermediate of Bioactive Substances, such as EGFR Kinase Inhibitors and LRRK2 Inhibitors
This product is used for the synthesis of bioactive substances, such as epidermal growth factor receptor (EGFR) kinase inhibitors for cancer, and leucine rich repeat kinase 2 (LRRK2) inhibitors for Parkinson's disease.
References
- Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors
- Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor
参考文献
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技术规格
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