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CAS RN: 1508-65-2 | 产品编码: O0451
Oxybutynin Hydrochloride
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纯度/分析方法: >98.0%(HPLC)
别名：
- 奥昔布宁盐酸盐
- α-苯基环己烷甘醇酸4-(二乙基氨基)-2-丁炔酯盐酸盐
- 环己基(羟基)苯基乙酸4-(二乙基氨基)-2-丁炔酯盐酸盐
- 4-(Diethylamino)-2-butynyl α-Phenylcyclohexaneglycolate Hydrochloride
- 4-(Diethylamino)-2-butyn-1-yl Cyclohexyl(hydroxy)phenylacetate Hydrochloride
- Cyclohexyl(hydroxy)phenylacetic Acid 4-(Diethylamino)-2-butyn-1-yl Ester Hydrochloride
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产品文档：
| 产品编码 | O0451 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__2__2H__3__1NO__3·HCl = 393.95 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 光,湿气 (吸湿) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 1508-65-2 |
| Reaxys-RN | 4833152 |
| PubChem物质ID | 468592520 |
| MDL编号 | MFCD00072150 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 96.0 % |
| Specific rotation [a]20/D | -0.1 to +0.1 deg(C=10, water) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 127 °C(dec.) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | GV2800000 |
运输信息
| HS编码* | 2922.19-000 |
应用
Oxybutynin chloride: A Muscarinic Receptor Antagonist with Spasmolytic Property
Oxybutynin chloride is an antispasmodic, muscarinic antagonist. It binds to M3 muscarinic receptors on the muscle of the bladder, preventing acetylcholinergic activation and relaxing the smooth muscle. In clinical, oxybutynin hydrochloride has been widely used for treating overactive bladder. Oxybutynin contains one asymmetric center, and the activity resides predominantly in the R-enantiomer. (The product is for research purpose only.)
References
- Human muscarinic receptor binding characteristics of antimuscarinic agents to treat overactive bladder
- Effects of 4-Ethylamino-2-butynyl(2-cyclohexyl-2-phenyl)glycolate Hydrochloride, a Metabolite of Oxybutynin, on Bladder Specimens and Rhythmic Bladder Contraction in Rats in Comparison With Oxybutynin
- Pharmacokinetics/Pharmacodynamics Analysis of the Relationship between the in Vivo Micturition Pressure and Receptor Occupancy of (R)-Oxybutynin and Its Metabolite in Rats
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