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CAS RN: 7729-94-4 | 产品编码: N1171
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
NMR | confirm to structure |
物性(参考值)
熔点 | 292 °C |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H302 : Harmful if swallowed. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
运输信息
HS编码* | 2924.29-000 |
应用
Norlidocaine (monoethylglycinexylidide: MEGX): A Main Active Metabolite of Lidocaine
Norlidocaine (monoethylglycinexylidide: MEGX) is a main active metabolite of lidocaine [L0156] formed by oxidative N-deethylation catalyzed by CYP1A2 and CYP3A4 in the liver, and its formation depends on liver microsomal activity. Therefore, the dynamic liver function test based on the hepatic conversion of lidocaine to MEGX (called MEGX test) has been used as a tool for the real-time assessment of hepatic function. (The product is for research purpose only.)
References
- Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans
- The MEGX test: a tool for the real-time assessment of hepatic function (a review)
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技术规格
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