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CAS RN: 475-83-2 | 产品编码: N1170
Nuciferine
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| 产品编码 | N1170 |
| 纯度/分析方法 | >97.0%(GC) |
| 分子式/分子量 | C__1__9H__2__1NO__2 = 295.38 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 475-83-2 |
| Reaxys-RN | 91202 |
| PubChem物质ID | 468592496 |
| MDL编号 | MFCD01664592 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 97.0 % |
| Specific rotation | -148 to -155 deg(C=0.5, EtOH) |
物性（参考值）
| 熔点 | 166 °C |
| 比旋光度 [α]D | -152° (C=0.5,EtOH) |
| 最大吸收波长 | 270(H2O) nm |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | CE0350000 |
运输信息
| UN编号 | UN1544 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2939.79-000 |
应用
Nuciferine: An Aporphine Alkaloid with Several Pharmacological Activities
Nuciferine is an aporphine alkaloid contained in lotus leaves (N. nucifera Gaertn), which is a raw material in Chinese medicinal herb for weight loss. Nuciferine has been reported to possess several pharmacological activities, including insulin secretagogue,1) anti-cancer,2,3) anti-hyperlipidemia4) and anti-inflammatory4) activities. (The product is for research purpose only.)
References
- 1) Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide
- 2) Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer
- 3) Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach
- 4) Nuciferine restores potassium oxonate-induced hyperuricemia and kidney inflammation in mice
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