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CAS RN: 288315-09-3 | 产品编码: M2742
Methylcobalamin Hydrate
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| 产品编码 | M2742 |
| 纯度/分析方法 | >98.0%(N) |
| 分子式/分子量 | C__6__3H__9__1CoN__1__3O__1__4P·xH__2O = 1,344.40 (as Anhydrous) |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 光,加热 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 288315-09-3 |
| 相关CAS RN | 13422-55-4 |
| Reaxys-RN | 18144941 |
| PubChem物质ID | 253661235 |
| MDL编号 | MFCD00082483 |
技术规格
| Appearance | Red to Dark red to Brown powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 12.0 % |
物性（参考值）
| 水溶性 | 微溶 |
GHS
相关法规
| RTECS# | GG3745000 |
运输信息
| HS编码* | 2936.26-000 |
应用
ビタミンB12の生理学的等価体，メチルコバラミン
Methylcobalamin, a water soluble vitamin B12 analog, is equivalent physiologically to vitamin B12. Methylcobalamin functions as a coenzyme in a number of reactions, including the oxidation of fatty acids and the synthesis of DNA. It also works in conjugation with folic acid [F0043] (Vitamin B9) in the synthesis of the amino acid L-methionine [M0099] and it required for normal production of red blood cells. Although methylcobalamin is necessary for nervous system maintenance, the mechanisms are not entirely known. Methylcobalamin can be used to prevent or treat pathology arising from a lack of vitamin B12. (The product is for research purpose only.)
References
- How a protein binds B12: a 3.0 Å x-ray structure of B12-binding domains of methionine synthase
- Similarities and Differences between Cobalamins and Cobaloximes. Accurate Structural Determination of Methylcobalamin and of LiCl- and KCl-Containing Cyanocobalamins by Synchrotron Radiation
- Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency (a review)
- Cobalamin-dependent methyltransferases (a review)
- Vitamin B12-derivatives - enzyme cofactors and ligands of proteins and nucleic acids (a review)
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